Studies on gene knockout in mice have shown that IL-7 plays a crucial role in the survival of lymphocytes. IL-7 stimulates pluripotent stem cells to differentiate into lymphoid progenitor cells.

Studies of the mouse counterpart suggested that IL-15 may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.

The biological effects of IL-21 include:inducing the differentiation of T-cell-stimulated B-cells into plasma cells and memory B-cells; the stimulation of IgG production in conjunction with IL-4;and the induction of apoptotic effects in naïve B-cells and stimulated B-cells in the absence of T-cell signaling.

Mononuclear cells isolated from peripheral blood, bone marrow, or umbilical cord blood can obtain large numbers of proliferating T lymphocytes in the presence of CD3 monoclonal antibodies and various cytokines.

By coupling anti-human CD3 and anti-human CD28 antibodies on magnetic beads, the primary and co-stimulatory signals needed to regulate T cell activation and expansion are provided.

Studies on gene knockout in mice have shown that IL-7 plays a crucial role in the survival of lymphocytes. IL-7 stimulates pluripotent stem cells to differentiate into lymphoid progenitor cells.

AMMS®MSC Cell Culture medium is a standardized, animal component- and serum-free media for the culture of Human mesenchymal stem cells and their primary progenitor cells (MSCs).

Mononuclear cells isolated from peripheral blood, bone marrow, or umbilical cord blood can obtain large numbers of proliferating T lymphocytes in the presence of CD3 monoclonal antibodies and various cytokines.

AMMS®MSC Cell Culture medium is a standardized, animal component- and serum-free media for the culture of Human mesenchymal stem cells and their primary progenitor cells (MSCs).

Suitable for human CIK cell culture, it has a large total cell count, high purity, high survival rate, and fast proliferation. At the same time, the phenotype of effector cells is also relatively stable.

The activation of CD137 can stimulate NK cell and T cell proliferation and generate anti-tumor activity, which produce durable memory responses.