Recombinant Human IL-7 Protein

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Product No.:GMP-TL506-0050

Product No.:100μg / GMP-TL506-0100

Product No.:GMP-TL506-1000(Customized)

Product Information

  • DMF filed no:


  • Expression Host:

    CHO cells

  • Synonym:


  • Protein sequence:

    A DNA sequence encoding the human IL-7(P13232-1:D26-H177)was expressed with a Fc-tag at the C-terminus.

  • Molecular Mass:

    The recombinant human IL-7 protein predicts a molecular mass of 43.8 kD.

  • QC Testing Purity:

    > 95 % as determined by SDS-PAGE and HPLC.

  • Endotoxin:

    < 0.01EU per 1μg of the protein by the LAL method.

  • Activity:

    Cell proliferation assay was performed on PBMC cells activated with CD3 monoclonal antibody, with an ED₅₀ of 0.5-20ng/mL and a corresponding specific activity of >1× 10⁷IU/mg (calibrated according to human IL-7 reference standard (NIBSC code: 90/530)).

  • Formulation:

    Lyophilized from sterile PBS, pH 7.4. Normally 6 % mannitol are added as protectants before lyophilization.

  • Stability:

    Lyophilized preparation can be stored at -20 ℃.
    6 months at -20℃ under sterile conditions after reconstitution.
    12 months at -80℃ under sterile conditions after reconstitution.

  • Storage:

    Recommend to aliquot the protein into smaller quantities after reconstituting with water for injection, normal saline or PBS, and keep the diluted concentration above 100μg/mL.
    Avoid repeated freeze-thaw cycles.


IL-7 is an important cytokine for the growth, survival, and differentiation of T, B, and NK cells. The heterodimer formed by IL-7 and hepatocyte growth factor (HGF) is a precursor B cell growth stimulating factor. Studies on gene knockout in mice have shown that IL-7 plays a crucial role in the survival of lymphocytes. IL-7 stimulates pluripotent stem cells to differentiate into lymphoid progenitor cells.

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